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The complex process of GETting tail-anchored membrane proteins to the ER
Biosynthesis of membrane proteins requires that hydrophobic transmembrane (TM) regions be shielded from the cytoplasm while being directed to the correct membrane. Tail-anchored (TA) membrane proteins, characterized by a single C-terminal TM, pose an additional level of complexity because they must...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3359790/ https://ncbi.nlm.nih.gov/pubmed/22444563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2012.03.001 |
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