Mechanism of Assembly of a Substrate Transfer Complex during Tail-anchored Protein Targeting

Tail-anchored (TA) proteins, defined as having a single transmembrane helix at their C terminus, are post-translationally targeted to the endoplasmic reticulum membrane by the guided entry of TA proteins (GET) pathway. In yeast, the handover of TA substrates is mediated by the heterotetrameric Get4/...

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Udgivet i:J Biol Chem
Main Authors: Gristick, Harry B., Rome, Michael E., Chartron, Justin W., Rao, Meera, Hess, Sonja, Shan, Shu-ou, Clemons, William M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Protein Structure and Folding
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705998/
https://ncbi.nlm.nih.gov/pubmed/26451041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.677328
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