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A molecular concept of the properdin pathway.

The sequential events of the properdin system were analyzed. Properdin-depleted serum allows the formation of a Factor B- and D-dependent C3 convertase. This enzyme, called the properdin-receptor-forming enzyme, was shown to utilize a novel serum component, the initiating factor. The protein is a be...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Medicus, R G, Schreiber, R D, Götze, O, Müller-Eberhard, H J
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1976
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC335961/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/54923/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.2.612
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