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Activation of the alternative complement pathway due to resistance of zymosan-bound amplification convertase to endogenous regulatory mechanisms.

The surface of zymosan (Zy), by affording a protected microenvironment for C3b and the amplification convertase stabilized by properdin, P,C3b,Bb, shifts the alternative complement pathway from slow fluid phase turnover to the amplification phase of its expression. This mode of activation is in cont...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Fearon, D T, Austen, K F
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1977
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC430857/
https://ncbi.nlm.nih.gov/pubmed/266208
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