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Activation of the alternative complement pathway due to resistance of zymosan-bound amplification convertase to endogenous regulatory mechanisms.

The surface of zymosan (Zy), by affording a protected microenvironment for C3b and the amplification convertase stabilized by properdin, P,C3b,Bb, shifts the alternative complement pathway from slow fluid phase turnover to the amplification phase of its expression. This mode of activation is in cont...

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Bibliografische gegevens
Hoofdauteurs: Fearon, D T, Austen, K F
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1977
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC430857/
https://ncbi.nlm.nih.gov/pubmed/266208
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