Chemotactic activity derived from interaction of factors D and B of the properdin pathway with cobra venom factor or C3B.

Interaction of D (the activated form of D) and B, factors of the properdin pathway, with C3b (the major cleavage fragment of C3) generates a convertase, C3B, which cleaves C3 and initiates the terminal complement sequence C5-C9. A functionally analogous more stable C3 convertase, CoVFB, ir formed by...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Ruddy, S, Austen, K F, Goetzl, E J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1975
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301787/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1167871/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI107966
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