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Chemotactic activity derived from interaction of factors D and B of the properdin pathway with cobra venom factor or C3B.

Interaction of D (the activated form of D) and B, factors of the properdin pathway, with C3b (the major cleavage fragment of C3) generates a convertase, C3B, which cleaves C3 and initiates the terminal complement sequence C5-C9. A functionally analogous more stable C3 convertase, CoVFB, ir formed by...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ruddy, S, Austen, K F, Goetzl, E J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1975
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC301787/
https://ncbi.nlm.nih.gov/pubmed/1167871
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