Chemotactic activity derived from interaction of factors D and B of the properdin pathway with cobra venom factor or C3B.
Interaction of D (the activated form of D) and B, factors of the properdin pathway, with C3b (the major cleavage fragment of C3) generates a convertase, C3B, which cleaves C3 and initiates the terminal complement sequence C5-C9. A functionally analogous more stable C3 convertase, CoVFB, ir formed by...
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| Udgivet i: | J Clin Invest |
|---|---|
| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
1975
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301787/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1167871/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI107966 |
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