Up-regulation of hypoxia inducible factor-1α by cobalt chloride correlates with proliferation and apoptosis in PC-2 cells

BACKGROUND: The exact mechanism of the effects of hypoxia on the proliferation and apoptosis in carcinoma cells is still conflicting. This study investigated the variation of hypoxia-inducible factor-1α(HIF-1α) expression and the apoptosis effect of hypoxia stimulated by cobalt chloride (CoCl(2)) in...

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Detalhes bibliográficos
Main Authors: Dai, Zhi-Jun, Gao, Jie, Ma, Xiao-Bin, Yan, Kun, Liu, Xiao-Xu, Kang, Hua-Feng, Ji, Zong-Zheng, Guan, Hai-Tao, Wang, Xi-Jing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359273/
https://ncbi.nlm.nih.gov/pubmed/22453051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-31-28
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