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Stabilization of hypoxia-inducible factor-1α in buffer containing cobalt chloride for Western blot analysis

Hypoxia-inducible factor-1α (HIF-1α) is a widely studied protein with significant biomedical impact. Care is needed to stabilize HIF-1α protein during sample preparation for Western blot analysis due to its rapid degradation in the presence of oxygen. Enzyme inhibitor cocktails can be complex and ex...

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Bibliografiske detaljer
Main Authors: Srinivasan, Sathyanarayanan, Dunn, Jeff F.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125494/
https://ncbi.nlm.nih.gov/pubmed/21601556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2011.04.037
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