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Protective effects of edaravone against cobalt chloride-induced apoptosis in PC12 cells

OBJECTIVE: To investigate the neuroprotective effects of edaravone (Eda) on cobalt chloride (CoCl(2))-induced oxidative stress and apoptosis in cultured PC12 cells as well as the underlying mechanisms. METHODS: PC12 cells impaired by CoCl(2) were used as the cell model of hypoxia. MTT (methyl thiazo...

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Pubblicato in:Neurosci Bull
Autori principali: Chen, Ji-Xiang, Zhao, Ting, Huang, Dan-Xia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552580/
https://ncbi.nlm.nih.gov/pubmed/19290025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-009-1215-6
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