Phosphorylation regulates human OCT4

The transcription factor OCT4 is fundamental to maintaining pluripotency and self-renewal. To better understand protein-level regulation of OCT4, we applied liquid chromatography–MS to identify 14 localized sites of phosphorylation, 11 of which were previously unknown. Functional analysis of two sit...

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Bibliografske podrobnosti
Main Authors: Brumbaugh, Justin, Hou, Zhonggang, Russell, Jason D., Howden, Sara E., Yu, Pengzhi, Ledvina, Aaron R., Coon, Joshua J., Thomson, James A.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2012
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358887/
https://ncbi.nlm.nih.gov/pubmed/22474382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203874109
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