Krüppel-like Factor 7 engineered for transcriptional activation promotes axon regeneration in the adult corticospinal tract

Axon regeneration in the central nervous system normally fails, in part because of a developmental decline in the intrinsic ability of CNS projection neurons to extend axons. Members of the KLF family of transcription factors regulate regenerative potential in developing CNS neurons. Expression of o...

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Autors principals: Blackmore, Murray G., Wang, Zimei, Lerch, Jessica K., Motti, Dario, Zhang, Yi Ping, Shields, Christopher B., Lee, Jae K., Goldberg, Jeffrey L., Lemmon, Vance P., Bixby, John L.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358880/
https://ncbi.nlm.nih.gov/pubmed/22529377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120684109
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