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Krüppel-like Factor 7 engineered for transcriptional activation promotes axon regeneration in the adult corticospinal tract

Axon regeneration in the central nervous system normally fails, in part because of a developmental decline in the intrinsic ability of CNS projection neurons to extend axons. Members of the KLF family of transcription factors regulate regenerative potential in developing CNS neurons. Expression of o...

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Bibliografische gegevens
Hoofdauteurs: Blackmore, Murray G., Wang, Zimei, Lerch, Jessica K., Motti, Dario, Zhang, Yi Ping, Shields, Christopher B., Lee, Jae K., Goldberg, Jeffrey L., Lemmon, Vance P., Bixby, John L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358880/
https://ncbi.nlm.nih.gov/pubmed/22529377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120684109
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