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Induction of microRNA-155 is TLR- and type IV secretion system-dependent in macrophages and inhibits DNA-damage induced apoptosis

Helicobacter pylori is a gastric pathogen responsible for a high disease burden worldwide. Deregulated inflammatory responses, possibly involving macrophages, are implicated in H. pylori-induced pathology, and microRNAs, such as miR-155, have recently emerged as crucial regulators of innate immunity...

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Bibliografiske detaljer
Main Authors: Koch, Manuel, Mollenkopf, Hans-Joachim, Klemm, Uwe, Meyer, Thomas F.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358876/
https://ncbi.nlm.nih.gov/pubmed/22509021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116125109
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