Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma

MicroRNA-155 (miR-155) is an oncogenic microRNA that regulates several pathways involved in cell division and immunoregulation. It is overexpressed in numerous cancers, is often correlated with poor prognosis, and is thus a key target for future therapies. In this work we show that overexpression of...

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Bibliografiske detaljer
Main Authors: Babar, Imran A., Cheng, Christopher J., Booth, Carmen J., Liang, Xianping, Weidhaas, Joanne B., Saltzman, W. Mark, Slack, Frank J.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387084/
https://ncbi.nlm.nih.gov/pubmed/22685206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201516109
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