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Probing the stability of nonglycosylated wild-type erythropoietin protein via reiterative alanine ligations
Nonglycosylated erythropoietin bearing acetamidomethyl protecting groups at the cysteine residues has been synthesized via chemical methods. Alanine ligation was used to assemble four peptide fragments, themselves prepared by solid phase peptide synthesis. This work outlines a route for the synthesi...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2012
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3358843/ https://ncbi.nlm.nih.gov/pubmed/22499784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1202762109 |
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