Inhibition of Integrin α2β1 Ameliorates Glomerular Injury

Mesangial cells and podocytes express integrins α1β1 and α2β1, which are the two major collagen receptors that regulate multiple cellular functions, including extracellular matrix homeostasis. Integrin α1β1 protects from glomerular injury by negatively regulating collagen production, but the role of...

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Autori principali: Borza, Corina M., Su, Yan, Chen, Xiwu, Yu, Ling, Mont, Stacey, Chetyrkin, Sergei, Voziyan, Paul, Hudson, Billy G., Billings, Paul C., Jo, Hyunil, Bennett, Joel S., DeGrado, William F., Eckes, Beate, Zent, Roy, Pozzi, Ambra
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2012
Soggetti:
Basic Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358756/
https://ncbi.nlm.nih.gov/pubmed/22440900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011040367
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