Drug Intake is Sufficient, but Conditioning is not Necessary for the Emergence of Compulsive Cocaine Seeking After Extended Self-Administration

Compulsive drug seeking, which is characterized by continued instrumental effort despite contingent punishment, has been shown to emerge after extended drug self-administration. Exactly what aspect of drug self-administration drives the appearance of addictive behavior is unclear, but the mechanisti...

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Autors principals: Jonkman, Sietse, Pelloux, Yann, Everitt, Barry J
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358752/
https://ncbi.nlm.nih.gov/pubmed/22334124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.6
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