Reduced Forebrain Serotonin Transmission is Causally Involved in the Development of Compulsive Cocaine Seeking in Rats

Whereas the majority of cocaine users quit as they experience the negative consequences of drug use, some lose control over their drug taking and compulsively seek drugs. We report that 20% of rats compulsively seek cocaine despite intermittent negative outcomes after escalating their cocaine self-a...

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Detalhes bibliográficos
Main Authors: Pelloux, Yann, Dilleen, Ruth, Economidou, Daina, Theobald, David, Everitt, Barry J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442345/
https://ncbi.nlm.nih.gov/pubmed/22763621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.111
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