Reduced Forebrain Serotonin Transmission is Causally Involved in the Development of Compulsive Cocaine Seeking in Rats

Whereas the majority of cocaine users quit as they experience the negative consequences of drug use, some lose control over their drug taking and compulsively seek drugs. We report that 20% of rats compulsively seek cocaine despite intermittent negative outcomes after escalating their cocaine self-a...

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Bibliografske podrobnosti
Main Authors: Pelloux, Yann, Dilleen, Ruth, Economidou, Daina, Theobald, David, Everitt, Barry J
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442345/
https://ncbi.nlm.nih.gov/pubmed/22763621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.111
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