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Cebranopadol Blocks the Escalation of Cocaine Intake and Conditioned Reinstatement of Cocaine Seeking in Rats

Cebranopadol is a novel agonist of nociceptin/orphanin FQ peptide (NOP) and opioid receptors with analgesic properties that is being evaluated in clinical Phase 2 and Phase 3 trials for the treatment of chronic and acute pain. Recent evidence indicates that the combination of opioid and NOP receptor...

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Pubblicato in:J Pharmacol Exp Ther
Autori principali: de Guglielmo, Giordano, Matzeu, Alessandra, Kononoff, Jenni, Mattioni, Julia, Martin-Fardon, Rémi, George, Olivier
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539589/
https://ncbi.nlm.nih.gov/pubmed/28645915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.241042
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