Determination of ribonuclease sequence-specificity using Pentaprobes and mass spectrometry

The VapBC toxin-antitoxin (TA) family is the largest of nine identified TA families. The toxin, VapC, is a metal-dependent ribonuclease that is inhibited by its cognate antitoxin, VapB. Although the VapBCs are the largest TA family, little is known about their biological roles. Here we describe a ne...

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Bibliographic Details
Main Authors: McKenzie, Joanna L., Duyvestyn, Johanna M., Smith, Tony, Bendak, Katerina, MacKay, Joel, Cursons, Ray, Cook, Gregory M., Arcus, Vickery L.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2012
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Method
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358648/
https://ncbi.nlm.nih.gov/pubmed/22539524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.031229.111
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