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VapC proteins from Mycobacterium tuberculosis share ribonuclease sequence specificity but differ in regulation and toxicity

The chromosome of Mycobacterium tuberculosis (Mtb) contains a large number of Type II toxin-antitoxin (TA) systems. The majority of these belong to the VapBC TA family, characterised by the VapC protein consisting of a PIN domain with four conserved acidic residues, and proposed ribonuclease activit...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Sharrock, Abigail, Ruthe, Alaine, Andrews, Emma S. V., Arcus, Vickery A., Hicks, Joanna L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6118392/
https://ncbi.nlm.nih.gov/pubmed/30169502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0203412
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