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Identification of the key residues determining the product specificity of isomerohydrolase
The efficient recycling of the chromophore of visual pigments, 11-cis retinal, through the retinoid visual cycle is an essential process for maintaining normal vision. RPE65 is the isomerohydrolase in retinal pigment epithelium and generates predominantly 11-cis retinol (11cROL) and a minor amount o...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3358571/ https://ncbi.nlm.nih.gov/pubmed/22512451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300144n |
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