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Complement protein C1q directs macrophage polarization and limits inflammasome activity during the uptake of apoptotic cells
Deficiency in C1q, the recognition component of the classical complement cascade and a pattern recognition receptor involved in apoptotic cell clearance, leads to lupus-like auto-immune diseases characterized by auto-antibodies to self proteins and aberrant innate immune cell activation likely due t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3358549/ https://ncbi.nlm.nih.gov/pubmed/22523386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103760 |
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