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Complement protein C1q directs macrophage polarization and limits inflammasome activity during the uptake of apoptotic cells

Deficiency in C1q, the recognition component of the classical complement cascade and a pattern recognition receptor involved in apoptotic cell clearance, leads to lupus-like auto-immune diseases characterized by auto-antibodies to self proteins and aberrant innate immune cell activation likely due t...

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Bibliografski detalji
Glavni autori: Benoit, Marie E., Clarke, Elizabeth V., Morgado, Pedro, Fraser, Deborah A., Tenner, Andrea J.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358549/
https://ncbi.nlm.nih.gov/pubmed/22523386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103760
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