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Complement protein C1q promotes macrophage anti-inflammatory M2-like polarization during the clearance of atherogenic lipoproteins

OBJECTIVE: Innate immune protein C1q plays a dual role in the chronic inflammatory disease of atherosclerosis. Complement activation via C1q exacerbates pathology in the atherosclerotic lesion in later stages of the disease. However, in early stages of disease C1q is protective. We hypothesize that...

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Bibliografische gegevens
Gepubliceerd in:Inflamm Res
Hoofdauteurs: Spivia, Weston, Magno, Patrick S., Le, Patrick, Fraser, Deborah A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154336/
https://ncbi.nlm.nih.gov/pubmed/25091012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00011-014-0762-0
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