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Complement protein C1q promotes macrophage anti-inflammatory M2-like polarization during the clearance of atherogenic lipoproteins

OBJECTIVE: Innate immune protein C1q plays a dual role in the chronic inflammatory disease of atherosclerosis. Complement activation via C1q exacerbates pathology in the atherosclerotic lesion in later stages of the disease. However, in early stages of disease C1q is protective. We hypothesize that...

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Bibliografiske detaljer
Udgivet i:Inflamm Res
Main Authors: Spivia, Weston, Magno, Patrick S., Le, Patrick, Fraser, Deborah A.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154336/
https://ncbi.nlm.nih.gov/pubmed/25091012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00011-014-0762-0
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