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Dental methacrylates may exert genotoxic effects via the oxidative induction of DNA double strand breaks and the inhibition of their repair

Methacrylate monomers used in dentistry have been shown to induce DNA double strand breaks (DSBs), one of the most serious DNA damage. In the present work we show that a model dental adhesive consisting of 45% 2-hydroxyethyl methacrylate (HEMA) and 55% bisphenol A-diglycidyl dimethacrylate (Bis-GMA)...

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Detalhes bibliográficos
Main Authors: Blasiak, Janusz, Synowiec, Ewelina, Tarnawska, Justyna, Czarny, Piotr, Poplawski, Tomasz, Reiter, Russel J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358545/
https://ncbi.nlm.nih.gov/pubmed/22327778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11033-012-1582-3
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