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2-Hydroxylethyl methacrylate (HEMA), a tooth restoration component, exerts its genotoxic effects in human gingival fibroblasts trough methacrylic acid, an immediate product of its degradation

HEMA (2-hydroxyethyl methacrylate), a methacrylate commonly used in dentistry, was reported to induce genotoxic effects, but their mechanism is not fully understood. HEMA may be degraded by the oral cavity esterases or through mechanical stress following the chewing process. Methacrylic acid (MAA) i...

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Detalhes bibliográficos
Main Authors: Szczepanska, Joanna, Poplawski, Tomasz, Synowiec, Ewelina, Pawlowska, Elzbieta, Chojnacki, Cezary J., Chojnacki, Jan, Blasiak, Janusz
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249584/
https://ncbi.nlm.nih.gov/pubmed/21617943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11033-011-0895-y
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