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2-Hydroxylethyl methacrylate (HEMA), a tooth restoration component, exerts its genotoxic effects in human gingival fibroblasts trough methacrylic acid, an immediate product of its degradation

HEMA (2-hydroxyethyl methacrylate), a methacrylate commonly used in dentistry, was reported to induce genotoxic effects, but their mechanism is not fully understood. HEMA may be degraded by the oral cavity esterases or through mechanical stress following the chewing process. Methacrylic acid (MAA) i...

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Main Authors: Szczepanska, Joanna, Poplawski, Tomasz, Synowiec, Ewelina, Pawlowska, Elzbieta, Chojnacki, Cezary J., Chojnacki, Jan, Blasiak, Janusz
格式: Artigo
語言:Inglês
出版: Springer Netherlands 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249584/
https://ncbi.nlm.nih.gov/pubmed/21617943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11033-011-0895-y
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