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Bone Marrow Stromal Cells Modulate Mouse ENT1 Activity and Protect Leukemia Cells from Cytarabine Induced Apoptosis

BACKGROUND: Despite a high response rate to chemotherapy, the majority of patients with acute myeloid leukemia (AML) are destined to relapse due to residual disease in the bone marrow (BM). The tumor microenvironment is increasingly being recognized as a critical factor in mediating cancer cell surv...

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Detalhes bibliográficos
Main Authors: Macanas-Pirard, Patricia, Leisewitz, Andrea, Broekhuizen, Richard, Cautivo, Kelly, Barriga, Francisco M., Leisewitz, Francisco, Gidi, Victoria, Riquelme, Erick, Montecinos, Viviana P., Swett, Pilar, Besa, Pelayo, Ramirez, Pablo, Ocqueteau, Mauricio, Kalergis, Alexis M., Holt, Matthew, Rettig, Michael, DiPersio, John F., Nervi, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358339/
https://ncbi.nlm.nih.gov/pubmed/22629369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037203
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