Low glucose under hypoxic conditions induces unfolded protein response and produces reactive oxygen species in lens epithelial cells

Aging is enhanced by hypoxia and oxidative stress. As the lens is located in the hypoglycemic environment under hypoxia, aging lens with diabetes might aggravate these stresses. This study was designed to examine whether low glucose under hypoxic conditions induces the unfolded protein response (UPR...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Elanchezhian, R, Palsamy, P, Madson, C J, Mulhern, M L, Lynch, D W, Troia, A M, Usukura, J, Shinohara, T
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2012
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358018/
https://ncbi.nlm.nih.gov/pubmed/22513875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.40
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