TIAF1 self-aggregation in peritumor capsule formation, spontaneous activation of SMAD-responsive promoter in p53-deficient environment, and cell death

Self-aggregation of transforming growth factor β (TGF-β)1-induced antiapoptotic factor (TIAF1) is known in the nondemented human hippocampus, and the aggregating process may lead to generation of amyloid β (Aβ) for causing neurodegeneration. Here, we determined that overexpressed TIAF1 exhibits as a...

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Main Authors: Chang, J-Y, Chiang, M-F, Lin, S-R, Lee, M-H, He, H, Chou, P-Y, Chen, S-J, Chen, Y-A, Yang, L-Y, Lai, F-J, Hsieh, C-C, Hsieh, T-H, Sheu, H-M, Sze, C-I, Chang, N-S
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358014/
https://ncbi.nlm.nih.gov/pubmed/22534828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.36
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