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PP2A inactivation is a crucial step in triggering apoptin-induced tumor-selective cell killing
Apoptin (apoptosis-inducing protein) harbors tumor-selective characteristics making it a potential safe and effective anticancer agent. Apoptin becomes phosphorylated and induces apoptosis in a large panel of human tumor but not normal cells. Here, we used an in vitro oncogenic transformation assay...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3358009/ https://ncbi.nlm.nih.gov/pubmed/22476099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.31 |
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