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Generation and replication-dependent dilution of 5fC and 5caC during mouse preimplantation development

One of the recent advances in the epigenetic field is the demonstration that the Tet family of proteins are capable of catalyzing conversion of 5-methylcytosine (5mC) of DNA to 5-hydroxymethylcytosine (5hmC). Interestingly, recent studies have shown that 5hmC can be further oxidized by Tet proteins...

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Библиографические подробности
Главные авторы: Inoue, Azusa, Shen, Li, Dai, Qing, He, Chuan, Zhang, Yi
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357997/
https://ncbi.nlm.nih.gov/pubmed/22124233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.189
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