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RNA Pol II as a sensor of 5caC

Cytosines in genomic DNA come in different flavors. A recent paper published in Nature reveals that an oxidized variety, 5-carboxylcytosine, is recognized by the elongating RNA polymerase, shedding light on the role of DNA oxidation in transcription regulation.

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Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Xue, Jian-Huang, Xu, Guo-Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650622/
https://ncbi.nlm.nih.gov/pubmed/26315484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2015.103
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