Mononuclear phagocyte intercellular crosstalk facilitates transmission of cell-targeted nanoformulated antiretroviral drugs to human brain endothelial cells

Despite the successes of antiretroviral therapy (ART), HIV-associated neurocognitive disorders remain prevalent in infected people. This is due, in part, to incomplete ART penetration across the blood–brain barrier (BBB) and lymph nodes and to the establishment of viral sanctuaries within the centra...

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Bibliografiske detaljer
Main Authors: Kanmogne, Georgette D, Singh, Sangya, Roy, Upal, Liu, Xinming, McMillan, JoEllyn, Gorantla, Santhi, Balkundi, Shantanu, Smith, Nathan, Alnouti, Yazen, Gautam, Nagsen, Zhou, You, Poluektova, Larisa, Kabanov, Alexander, Bronich, Tatiana, Gendelman, Howard E
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2012
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357981/
https://ncbi.nlm.nih.gov/pubmed/22661891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S29454
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