Mononuclear phagocyte intercellular crosstalk facilitates transmission of cell-targeted nanoformulated antiretroviral drugs to human brain endothelial cells

Despite the successes of antiretroviral therapy (ART), HIV-associated neurocognitive disorders remain prevalent in infected people. This is due, in part, to incomplete ART penetration across the blood–brain barrier (BBB) and lymph nodes and to the establishment of viral sanctuaries within the centra...

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Autori principali: Kanmogne, Georgette D, Singh, Sangya, Roy, Upal, Liu, Xinming, McMillan, JoEllyn, Gorantla, Santhi, Balkundi, Shantanu, Smith, Nathan, Alnouti, Yazen, Gautam, Nagsen, Zhou, You, Poluektova, Larisa, Kabanov, Alexander, Bronich, Tatiana, Gendelman, Howard E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2012
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357981/
https://ncbi.nlm.nih.gov/pubmed/22661891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S29454
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