Analyses of Nanoformulated Antiretroviral Drug Charge, Size, Shape and Content for Uptake, Drug Release and Antiviral Activities in Human Monocyte-Derived Macrophages

Long-term antiretroviral therapy (ART) for human immunodeficiency virus type one (HIV-1) infection shows limitations in pharmacokinetics and biodistribution while inducing metabolic and cytotoxic aberrations. In turn, ART commonly requires complex dosing schedules and leads to the emergence of viral...

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Main Authors: Nowacek, Ari S., Balkundi, Shantanu, McMillan, JoEllyn, Roy, Upal, Martinez-Skinner, Andrea, Mosley, R. Lee, Kanmogne, Georgette, Kabanov, Alexander V., Bronich, Tatiana, Gendelman, Howard E.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065529/
https://ncbi.nlm.nih.gov/pubmed/21108978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2010.11.019
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