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UNC-4 antagonizes Wnt signaling to regulate synaptic choice in the C. elegans motor circuit

Coordinated movement depends on the creation of synapses between specific neurons in the motor circuit. In C. elegans, this important decision is regulated by the UNC-4 homeodomain protein. unc-4 mutants are unable to execute backward locomotion because VA motor neurons are mis-wired with inputs nor...

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Bibliografske podrobnosti
Main Authors: Schneider, Judsen, Skelton, Rachel L., Von Stetina, Stephen E., Middelkoop, Teije C., van Oudenaarden, Alexander, Korswagen, Hendrik C., Miller, David M.
Format: Artigo
Jezik:Inglês
Izdano: Company of Biologists 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357913/
https://ncbi.nlm.nih.gov/pubmed/22619391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.075184
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