UNC-4 antagonizes Wnt signaling to regulate synaptic choice in the C. elegans motor circuit

Coordinated movement depends on the creation of synapses between specific neurons in the motor circuit. In C. elegans, this important decision is regulated by the UNC-4 homeodomain protein. unc-4 mutants are unable to execute backward locomotion because VA motor neurons are mis-wired with inputs nor...

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Main Authors: Schneider, Judsen, Skelton, Rachel L., Von Stetina, Stephen E., Middelkoop, Teije C., van Oudenaarden, Alexander, Korswagen, Hendrik C., Miller, David M.
格式: Artigo
語言:Inglês
出版: Company of Biologists 2012
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Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357913/
https://ncbi.nlm.nih.gov/pubmed/22619391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.075184
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