UNC-4 antagonizes Wnt signaling to regulate synaptic choice in the C. elegans motor circuit

Coordinated movement depends on the creation of synapses between specific neurons in the motor circuit. In C. elegans, this important decision is regulated by the UNC-4 homeodomain protein. unc-4 mutants are unable to execute backward locomotion because VA motor neurons are mis-wired with inputs nor...

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Detalhes bibliográficos
Main Authors: Schneider, Judsen, Skelton, Rachel L., Von Stetina, Stephen E., Middelkoop, Teije C., van Oudenaarden, Alexander, Korswagen, Hendrik C., Miller, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357913/
https://ncbi.nlm.nih.gov/pubmed/22619391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.075184
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