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UNC-4 antagonizes Wnt signaling to regulate synaptic choice in the C. elegans motor circuit

Coordinated movement depends on the creation of synapses between specific neurons in the motor circuit. In C. elegans, this important decision is regulated by the UNC-4 homeodomain protein. unc-4 mutants are unable to execute backward locomotion because VA motor neurons are mis-wired with inputs nor...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Schneider, Judsen, Skelton, Rachel L., Von Stetina, Stephen E., Middelkoop, Teije C., van Oudenaarden, Alexander, Korswagen, Hendrik C., Miller, David M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Company of Biologists 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357913/
https://ncbi.nlm.nih.gov/pubmed/22619391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.075184
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