UNC-4 antagonizes Wnt signaling to regulate synaptic choice in the C. elegans motor circuit

Coordinated movement depends on the creation of synapses between specific neurons in the motor circuit. In C. elegans, this important decision is regulated by the UNC-4 homeodomain protein. unc-4 mutants are unable to execute backward locomotion because VA motor neurons are mis-wired with inputs nor...

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Библиографические подробности
Главные авторы: Schneider, Judsen, Skelton, Rachel L., Von Stetina, Stephen E., Middelkoop, Teije C., van Oudenaarden, Alexander, Korswagen, Hendrik C., Miller, David M.
Формат: Artigo
Язык:Inglês
Опубликовано: Company of Biologists 2012
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Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357913/
https://ncbi.nlm.nih.gov/pubmed/22619391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.075184
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