Function of Wnt/β-catenin in counteracting Tcf3 repression through the Tcf3–β-catenin interaction

The canonical Wnt/β-catenin signaling pathway classically functions through the activation of target genes by Tcf/Lef–β-catenin complexes. In contrast to β-catenin-dependent functions described for Tcf1, Tcf4 and Lef1, the known embryonic functions for Tcf3 in mice, frogs and fish are consistent wit...

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Bibliografiske detaljer
Main Authors: Wu, Chun-I, Hoffman, Jackson A., Shy, Brian R., Ford, Erin M., Fuchs, Elaine, Nguyen, Hoang, Merrill, Bradley J.
Format: Artigo
Sprog:Inglês
Udgivet: Company of Biologists 2012
Fag:
Development and Stem Cells
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357906/
https://ncbi.nlm.nih.gov/pubmed/22573616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.076067
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