Opposing Effects of Tcf3 and Tcf1 Control Wnt-Stimulation of Embryonic Stem Cell Self Renewal

The observation that Tcf3 (MGI name: Tcf7l1) bound the same genes as core stem cell transcription factors, Oct4 (MGI name:Pou5f1), Sox2 and Nanog, revealed a potentially important aspect of the poorly understood mechanism whereby Wnts stimulate self renewal of pluripotent mouse embryonic stem (ES) c...

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Bibliografiske detaljer
Main Authors: Yi, Fei, Pereira, Laura, Hoffman, Jackson A., Shy, Brian R., Yuen, Courtney M., Liu, David R., Merrill, Bradley J.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129424/
https://ncbi.nlm.nih.gov/pubmed/21685894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2283
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