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HESX1- and TCF3-mediated repression of Wnt/β-catenin targets is required for normal development of the anterior forebrain

The Wnt/β-catenin pathway plays an essential role during regionalisation of the vertebrate neural plate and its inhibition in the most anterior neural ectoderm is required for normal forebrain development. Hesx1 is a conserved vertebrate-specific transcription factor that is required for forebrain d...

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Bibliographic Details
Main Authors: Andoniadou, Cynthia L., Signore, Massimo, Young, Rodrigo M., Gaston-Massuet, Carles, Wilson, Stephen W., Fuchs, Elaine, Martinez-Barbera, Juan Pedro
Format: Artigo
Language:Inglês
Published: Company of Biologists 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201662/
https://ncbi.nlm.nih.gov/pubmed/22007134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.066597
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