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Intracellular Loop 2 Peptides of the Human 5HT1a Receptor are Differential Activators of Gi

Peptide mimics of intracellular loop 2 (ic2) of the human 5HT1a receptor have been studied with respect to their ability to inhibit agonist binding via interference with receptor-G-protein coupling. These peptides give shallow concentration-effect relationships. Additionally, these peptides have bee...

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Bibliografiske detaljer
Main Authors: Hall, Brian, Squires, Carley, Parker, Keith K.
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357532/
https://ncbi.nlm.nih.gov/pubmed/22649462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/490734
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