Thermodynamics of Peptide and Non-Peptide Interactions with the Human 5HT1a Receptor

The human serotonin 1a receptor (H5HT1aR) is a highly studied member of the 7 transmembrane G protein-coupled receptors. This model receptor, negatively coupled to adenylyl cyclase via Gi, is linked to physiological processes such as cognition and mood regulation and to associated disorders like anx...

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Main Authors: Hall, Brian, Burnett, Andrea, Christians, Alicia, Halley, Cortney, Goldstein, Eric, Thiagaraj, Harish V., Parker, Keith K.
Formato: Artigo
Idioma:Inglês
Publicado: S. Karger AG 2010
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Original Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214922/
https://ncbi.nlm.nih.gov/pubmed/20559018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000312684
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