Preexisting Autoantibodies Predict Efficacy of Oral Insulin to Cure Autoimmune Diabetes in Combination With Anti-CD3

We have previously developed a combination therapy (CT) using anti-CD3 monoclonal antibodies together with islet-(auto)antigen immunizations that can more efficiently reverse type 1 diabetes (T1D) than either entity alone. However, clinical translation of antigen-specific therapies in general is ham...

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Autors principals: Mamchak, Alusha A., Manenkova, Yulia, Leconet, Wilhem, Zheng, Yanan, Chan, Jason R., Stokes, Cynthia L., Shoda, Lisl K.M., von Herrath, Matthias, Bresson, Damien
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2012
Matèries:
Immunology and Transplantation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357270/
https://ncbi.nlm.nih.gov/pubmed/22362174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1304
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