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Nonviral Delivery of Small Interfering RNA Into Pancreas-associated Immune Cells Prevents Autoimmune Diabetes

The development of small interfering RNA (siRNA) for the treatment of human disorders has been often hampered by their low transfection efficiency in vivo. In order to overcome this major drawback, various in vivo siRNA transfection methods have been developed. However, their capacity to transfect i...

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Detalhes bibliográficos
Main Authors: Leconet, Wilhem, Petit, Pierre, Peraldi-Roux, Sylvie, Bresson, Damien
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519991/
https://ncbi.nlm.nih.gov/pubmed/22990670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.190
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