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Upf1 ATPase-dependent mRNP disassembly is required for completion of nonsense-mediated mRNA decay

Cellular mRNAs exist in messenger ribonucleoprotein (mRNP) complexes, which undergo transitions during the lifetime of the mRNAs and direct posttranscriptional gene regulation. A final posttranscriptional step in gene expression is the turnover of the mRNP, which involves degradation of the mRNA and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Franks, Tobias M., Singh, Guramrit, Lykke-Andersen, Jens
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357093/
https://ncbi.nlm.nih.gov/pubmed/21145460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.11.043
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