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PROTEIN THERAPEUTICS FOR JUNCTIONAL EPIDERMOLYSIS BULLOSA: INCORPORATION OF RECOMBINANT β3 CHAIN INTO LAMININ 332 IN β3-/- KERATINOCYTES IN VITRO

Junctional epidermolysis bullosa (JEB) is an inherited mechanobullous disease characterized by reduced adherence of the epidermal keratinocytes to the underlying dermis and often caused by the absence of functional laminin 332 due to the lack or dysfunction of its β3 chain. As there are no specific...

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Détails bibliographiques
Auteurs principaux: Igoucheva, Olga, Kelly, Aislinn, Uitto, Jouni, Alexeev, Vitali
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357058/
https://ncbi.nlm.nih.gov/pubmed/18079746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.jid.5701197
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